Research Articles
The Alpha Cell Enigma: How a Diabetes Drug Reveals New Secrets of Glucagon
Exploring the paradoxical effect of SGLT2 inhibitors on glucagon secretion and the scientific debate surrounding pancreatic alpha cell biology.
The Sugar Switch: How a Newborn Calf's Liver Masters Glucose Control
Explore the delicate hormonal dance that keeps a newborn calf alive and thriving through gluconeogenesis regulation by insulin and glucagon.
The Accidental Messenger: How a Blood Pressure Drug Talks to Your Hormones
Discover how clonidine, a blood pressure medication, unexpectedly influences growth hormone and glucagon secretion in the human body.
Taming the Sugar Signal: How a Lab-Made Antibody Put the Brakes on Diabetes
Discover how scientists used a monoclonal antibody to block glucagon receptors and restore metabolic balance in diabetic mice through PK/PD modeling.
The Missing Switch: What Mutant Mice Teach Us About Diabetes
Discover how glucagon receptor knockout mice revolutionized our understanding of diabetes and blood sugar regulation.
Avian Biology to the Rescue: How Chicken Hormones Could Revolutionize Diabetes Treatment
Discover how chicken hormones and the GCGR family could transform diabetes treatment through cross-species biological mechanisms.